Leukocyte – Platelet Rich Fibrin (L-PRF), Alternative for Bone Grafting

Patients with insufficient bone mass that want a full mouth restoration or dental implants often require a bone graft to ensure that there is enough bone to support their new dental work. However beneficial, bone grafts can be expensive and are often out of reach for budget-conscious patients. Cutting edge dental technology and dental science have produced another option that may be the ideal alternative solution for bone graft patients.

Leukocyte – Platelet Rich Fibrin (L-PRF) is a 100% natural – autologous graft derived from the patient’s blood. A very simple procedure allows the dentist to obtain a thin, compressed layer of platelet rich fibrin. This fibrin network is rich in platelets, growth factors and cytokines that are derived from the blood platelets and leukocytes. L-PRF helps speed growth of both soft tissue and bone where injected, reducing the need for bone grafts.

First developed and successfully tested in France, L-PRF is a simple and inexpensive technique for the successful regeneration of soft and hard dental tissues. Instead of painful bone grafts or the dangers associated with bovine grafts, L-PRF utilizes the patient’s own blood reducing or eliminating disease transmission through blood.

L-PRF Applications Include Treatments for:

  • Dental Implants.
  • Bone Defects.
  • Tooth Extraction Sockets.
  • Sinus and Dental Ridge Augmentation.
  • Palate Defects.
  • Jaw Bone Atrophy.

L-PRF Benefits:

  • 100% natural – autologous graft.
  • Simple and very economic procedure when compared to bone grafts.
  • L-PRF produces rapid healing, especially during the critical first seven days after placement.
  • L-PRF promotes more efficient cell migration and proliferation without chemical or bovine thrombin additives.

L-PRF has been clinically tested and has demonstrated the following traits:

  • Is resilient, strong and flexible, making it easy to manipulate.
  • It can be cut to size and is flexible enough to adapt to many anatomical areas.
  • It’s adhesive by nature and very receptive to suture.
  • It has a flexible use span. L-PRF is stable at room temperature for several hours.
  • It can be mixed with autograft and/or allograft bone prior to application to improve healing characteristics.

L-PRF is developed with a simple three-step processing protocol:

  • Blood sample collection (drawing blood)
  • Spinning blood at the Centrifuge IntraSpin System
  • Expressing the fibrin clot in the fabrication kit device and compressed layer of Platelet Rich Fibrin of a consistent thickness.


Fill out the “Help me find a Dentist” form to the right and Costa Rica Dental Guide will contact you to tell you more about L-PRF and the benefits of incorporating L-PRF for your full mouth restoration or dental implant work.